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Table 2 GO analysis of up-regulated and down-regulated DEGs

From: Identification of differentially expressed genes, signaling pathways and immune infiltration in rheumatoid arthritis by integrated bioinformatics analysis

ID Description Adjusted P-values Gene symbol Count
Up-regulated
GO:0004896 cytokine receptor activity 8.17E-09 IL21R/IL7R/IL2RG/CCR5/CCR2/CSF2RB/CCR7/CXCR4/CXCR6/CXCR3/CD4/CCR1/IL2RA/IL15RA/CX3CR1/CD74/CCRL2/IL1RL1/CXCR5/CCR6 20
GO:0001637 G protein-coupled chemoattractant receptor activity 1.30E-07 CCR5/CCR2/CCR7/CXCR4/CXCR6/CXCR3/CCR1/CX3CR1/CCRL2/CXCR5/CCR6 11
GO:0004950 chemokine receptor activity 1.30E-07 CCR5/CCR2/CCR7/CXCR4/CXCR6/CXCR3/CCR1/CX3CR1/CCRL2/CXCR5/CCR6 11
GO:0023023 MHC protein complex binding 1.30E-07 HLA-DOB/MS4A1/CD8A/HLA-DMB/HLA-DMA/KLRD1/LILRB2/LILRB1/HLA-DRA/TAPBPL/CD74 11
GO:0019956 chemokine binding 7.20E-07 ITGA4/CCR5/CCR2/CCR7/CXCR4/CXCR6/CXCR3/CCR1/CX3CR1/CCR6 10
Down-regulated
GO:0004601 peroxidase activity 0.044092206 DUOX2/GPX3/PTGS2 3
GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 0.044092206 DUOX2/GPX3/PTGS2 3
  1. GO gene ontology, DEGs differentially expressed genes
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Hereditas

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