Relationship between circulating miR-132 and non-alcoholic fatty liver disease in a Chinese population

Hereditas

Table 1 Anthropometric parameters and clinical characteristics of participants

	Non-diabetes group		P values	Diabetic group		P value
	Control (N = 67)	NAFLD (N = 73)	P values	Control (N = 68)	NAFLD (N = 66)	P value
Age (years)	57.87 ± 6.84	57.28 ± 6.66	0.605	57.74 ± 6.83	57.21 ± 6.46	0.647
Male/female (n)	47/20	50/23	0.832	46/22	46/20	0.798
BMI (kg/m²)	24.39 ± 1.96	24.89 ± 2.14	0.156	57.74 ± 6.83	57.21 ± 6.46	0.647
FPG (mmol/L)	5.56 ± 0.47	5.82 ± 0.50	0.002	7.22 ± 1.29	7.15 ± 1.31	0.757
2 h PG (mmol/L)	7.04 ± 1.61	8.03 ± 1.64	< 0.001	12.95 ± 3.69	12.85 ± 3.31	0.87
HbA1C (%)	5.58 ± 0.31	5.59 ± 0.40	0.778	6.17 ± 1.12	6.45 ± 0.83	0.108
ALT (U/L)	20.58 ± 5.40	33.52 ± 13.84	< 0.001	16.59 ± 6.96	23.14 ± 10.96	< 0.001
AST (U/L)	22.81 ± 5.17	27.51 ± 9.03	< 0.001	21.09 ± 5.25	23.03 ± 5.54	0.039
GGT (U/L)	22.85 ± 8.00	47.56 ± 28.84	< 0.001	22.76 ± 9.04	35.98 ± 23.31	< 0.001
TG (mmol/L)	1.25 ± 0.60	2.02 ± 1.11	< 0.001	1.38 ± 0.77	1.98 ± 1.13	< 0.001
TC (mmol/L)	5.19 ± 0.93	5.35 ± 1.02	0.350	4.97 ± 0.90	5.34 ± 0.93	0.021
LDL-C (mmol/L)	3.24 ± 0.77	3.36 ± 0.84	0.357	3.03 ± 0.75	3.36 ± 0.75	0.012
HDL-C(mmol/L)	1.36 ± 0.29	1.22 ± 0.24	0.002	1.28 ± 0.26	1.24 ± 0.29	0.349
APOA (mmol/L)	1.39 ± 0.28	1.4 ± 0.26	0.783	1.45 ± 0.30	1.38 ± 0.33	0.179
APOB (mmol/L)	0.89 ± 0.17	0.93 ± 0.17	0.093	0.87 ± 0.15	0.94 ± 0.15	0.068
APOE (mmol/L)	4.26 ± 1.56	5.07 ± 2.01	0.009	4.34 ± 1.77	4.85 ± 1.66	0.090
FFA (umol/L)	503.16 ± 185.25	528.46 ± 152.50	0.382	647.09 ± 249.14	640.25 ± 244.14	0.874

Data are shown as mean ± standard deviation. P value indicates the comparison of non-alcoholic fatty liver disease (NAFLD) and control subjects
Abbreviations: 2hPG 2-h plasma glucose, FPG Fasting plasma glucose, ALT Aspartate aminotransferase, AST Alanine aminotransferase, ALT Alanine aminotransferase, TG Triglyceride, TC Total cholesterol, APOE Apolipoprotein E, APOA Apolipoprotein A, APOA Apolipoprotein A, HDL-C High-density lipoprotein cholesterol, LDL-C Low-density lipoprotein cholesterol, FFA Free fatty acids

ISSN: 1601-5223